Vitamin A deficiency in pre-school age Congolese children during malarial
attacks. Part 2: Impact of parasitic disease on vitamin A status.
Galan P; Samba C; Luzeau R; Amedee-Manesme O
Int J Vitam Nutr Res 1990;60(3):224-8
The vitamin A status of 454
pre-school age Congolese children was evaluated by the impression cytology
method with transfer (ICT) and by the determination of plasma retinol.
During malarial attacks, the vitamin A status is abnormal (deficient or
marginal) in 40.8% of the children according to the ICT test and in 37.5%
of the children who have plasma levels of retinol lower than 10 micrograms/dl.
The mean concentration of plasma retinol in patients during malarial attacks
(14.8 +/- 9.5 micrograms/dl) is significantly lower than the values found
in other subjects (31.5 +/- 14.3 micrograms/dl) (p less than 0.001). A
significant correlation was established between the results of the ICT
test and two biochemical parameters (retinol, transthyretin). We conclude
that there is a significant relationship between vitamin A deficiency
and a malarial attack.