BONE LOSS – VITAMIN C
Anderson JW; Gowri MS; Turner J; Nichols L; Diwadkar VA; Chow CK; Oeltgen
PR, J Am Coll Nutr 1999 Oct;18(5):451-61
"The Relation of Dietary Vitamin C Intake to Bone Mineral Density:
Results From the PEPI Study," Hall SL and Greendale GA, Calcified
Tissue International, 1998;63:183-189.
In evaluating 775 women
between 45 and 64 years of age, it was found for each 100 mg increment
in dietary vitamin C intake, there was an associated 0.017 g/cm2 increment
in bone mineral density (BMD). After adjusting for variables,
the association of vitamin C with lumbar spine BMD was similar to that
at the hip, but was not statistically significant. Among women ingesting
a higher amount of calcium, there was a statistically significant association
between vitamin C and lumbar spine BMD. These data suggest a positive
association of vitamin C with BMD in postmenopausal women with
dietary calcium intakes of at least 500 mg per day.