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"The Relation of Dietary Vitamin C Intake to Bone Mineral Density: Results From the PEPI Study," Hall SL and Greendale GA, Calcified Tissue International, 1998;63:183-189.

Anderson JW; Gowri MS; Turner J; Nichols L; Diwadkar VA; Chow CK; Oeltgen PR, J Am Coll Nutr 1999 Oct;18(5):451-61

In evaluating 775 women between 45 and 64 years of age, it was found for each 100 mg increment in dietary vitamin C intake, there was an associated 0.017 g/cm2 increment in bone mineral density (BMD). After adjusting for variables, the association of vitamin C with lumbar spine BMD was similar to that at the hip, but was not statistically significant. Among women ingesting a higher amount of calcium, there was a statistically significant association between vitamin C and lumbar spine BMD. These data suggest a positive association of vitamin C with BMD in postmenopausal women with dietary calcium intakes of at least 500 mg per day.



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