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Scientific publications by
Dr. A. Niedzwiecki

A Specific Combination Of Ascorbic Acid, Lysine, Proline And Epigallocatechin Gallate Inhibits Proliferation And Extracellular Matrix Invasion Of Various Human Cancer Cell Lines
Shrirang P Netke, M Waheed Roomi, Vadim Ivanov, Aleksandra Niedzwiecki* and Matthias Rath
Matthias Rath, Inc., Research and Development, Santa Clara, CA 95054

Cytotxic Effect of Lipophlic Substitution at 2-, 6-, and 2,6-Positions in Ascorbic Acid and Expression of Matrix Metalloproteinases in Hep G2 Cells, Melanoma Cells and Norman Human Dermal Fibroblast.
M.W. Roomi, S. Netke, V. Ivanov, A. Niedzwiecki and M. Rath
J. Am. Coll. Nutr. 20: 43, 2001

Inhibitory effects of ascorbic acid, proline and lysine supplementation on Matrigel invasion by human breast cancer cells, MDA-MB231.
S Netke, Ph.D., V Ivanov , MD. Ph.D., W. Roomi, Ph. D., A Niedzwiecki, Ph. D., Matthias Rath, M.D.
Presented at: 19th Annual Miami Breast Cancer Conference, Miami Beach, Florida, February 27 – March 3, 2002. Published in: Conference Proceedings

Cellular Medicine Research Breakthroughs in the Control of Diseases: Report on Scientific Research
S Netke, Ph.D., V Ivanov , MD. Ph.D., W. Roomi, Ph. D., A Niedzwiecki, Ph. D., Matthias Rath, M.D.
Presented at: 21st Century Medical Advances in the Treatment of Cancer and Aging, Miami , Fl, March 22-24, 2003; Published in: Conference Proceedings

Metastatic and Cytotoxic Effects of Ascorbigen and iso-Ascorbigen in Human Cancer Cell Lines.
M.W. Roomi, A. Bogale, V. Ivanov, S. Netke, A. Niedzwiecki and M. Rath,
J. Am. Coll. Nut. 21: 54, 2002

Matrix Metalloproteinase-2 Inhibition and Invasion Potential in Human Chondrocytes by a natural anti-cancer formula - a Specific Mixture of Nutrients Containing Lysine, Proline, Ascorbic Acid and Epigallocatechin Gallate.
M.W. Roomi, S.P. Netke, V. Ivanov, M. Rath and A. Niedzwiecki
Presented at: American Association of Cancer Research Special Conference in Cancer Research: Proteases, Extracellular Matrix and Cancer, Hilton Head Island, South Carolina, Oct 9-13, 2002.

Epican Forte - A Specific Formulation of Nutrients Containing Lysine,Proline, Ascorbic Acid, and Epigallocatechin Gallate Inhibits Matrix Metalloproteinases Activity and Invasion Potential of Human Cancer Cell Lines.
M.W. Roomi, S.P. Netke, V. Ivanov, M. Rath and A. Niedzwiecki
Presented at: European Organization for Research and Treatment of Cancer (EORTC), AACR and NCI Symposium on Molecular Targets and Cancer Therapeutics, Frankfurt, Germany, Nov 19-22, 2002; Published in: European Cancer Journal, 38, Suppl.7/Abs.280, 2002

A Natural Anti-Cancer Formula - A Specific Formulation of Nutrients Containing Lysine,Proline, Ascorbic Acid, and Epigallocatechin Gallate Inhibits Matrix Metalloproteinases Activity and Invasion Potential of Human Cancer Cell Lines.
M.W. Roomi, S.P. Netke, V. Ivanov, M. Rath and A. Niedzwiecki
Presented at: European Organization for Research and Treatment of Cancer (EORTC), AACR and NCI Symposium on Molecular Targets and Cancer Therapeutics, Frankfurt, Germany, Nov 19-22, 2002; Published in: European Cancer Journal, 38, Suppl.7/Abs.280, 2002

Antitumorigenic Activity of a Natural Anti-Cancer Formula in Human Breast Cancer Lines MDA-MB-231 and MCF-7.
Roomi, M.W., Ivanov, V., Rath, M. and Niedzwiecki, A.
Presented at: The 8th Annual Multidisciplinary Symposium on Breast Disease, Amelia Island, FL, February 13-16, 2003; Published in: Conference Proceedings

A randomized, double-blind placebo-controlled clinical study documents the benefits of a vitamin program as an adjunct therapy in patients with paraxysmal atrial arrhytmia.
Matthias Rath M.D. and Aleksandra Niedzwiecki Ph.D.
14th Madrid Arrhytmia Meeting, Madrid, Spain, February 27-28, 2003

A novel in vitro bioassay for screening matrix metalloproteinases activity in human cancer cell lines
M Waheed Roomi, Shirang P Netke, Vadim Ivanov, Matthias Rath and Aleksandra Niedzwiecki
Proceedings of the American Association for Cancer Research 44:4559(2003)

Inhibitory Effect of a Natural Anti-Cancer Formula - A Specific Formulation of Nutrients Containing Lysine, Proline, Ascorbic Acid and Epigallocatechin Gallate on the Matrix Metalloproteinases Activities and Invasion of Human Fibrosarcoma HT-1080 Cells
MW Roomi, V Ivanov, SP Netke, M Rath and A Niedzwiecki
FASEB Journal (2003) 8452

Letter to Editor: Antioxidant supplements and simvastatin-niacin therapy.
Netke S, Ivanov V, Roomi W, Niedzwiecki A, Rath M.
Arterioscler Thromb Vasc Biol. (2001) 21, 2099-2100.

Expression of Bovine Superoxide Dismutase in Drosophila.
Augments Resistance to Oxidative Stress

I.Reveillaud, A.Niedzwiecki, K.G.Bensch, J.E.Fleming.
Mol.Cell.Biol. 11, 1026-1030. (1991)

Changes in Superoxide Dismutase and Catalase in Aging Heat-shocked Drosophila
A.Niedzwiecki, I.Reveillaud, J.E.Fleming
Free Rad. Res. Commun. 17, 355-367. (1992)

Role of oxidative stress in Drosophila aging.
J.E.Fleming, I.Reveillaud, A.Niedzwiecki
Mutat. Res. 275, 267-279 (1992)

Heat shock induces changes in the expression and binding of ubiquitin in senescent Drosophila melanogaster
A. Niedzwiecki, J.E.Fleming
Dev. Genet., 14, 78-86. (1993)

Stress Induced Expression of Cu/Zn Superoxide Dismutase and Catalase in Senescent Drosophila melanogaster. in New Strategies in Prevention and Therapy.
J.E.Fleming, A. Niedzwiecki, I.Reveillaud
Biological Oxidants and Antioxidants., K. Schmidt (ed.), Hippokrates Verlag, Stuttgart, pp.181-192. (1994)

Ascorbic Acid Protects Guinea Pigs from Acute Aflatoxin Toxicity
P. Netke, W. Roomi, C. Tsao, A. Niedzwiecki
, J. Toxicol. 143, 429-435. (1997)

Ascorbate Affects Proliferation of Guinea Pigs Vascular Smooth Muscle Cells by Direct and Extracellular Matrix Mediated Effects
V. O.Ivanov, S. Ivanova, A. Niedzwiecki
J.Mol.Cell.Cardiol. 29, 3293-3303 (1997)

Transforming Growth Factor-Beta 1 and Ascorbate Regulate Proliferation of Cultured Smooth Muscle Cells by Independent Mechanisms
V. Ivanov, A.B. Rabovsky, S.V. Ivanova, A. Niedzwiecki
Atherosclerosis 140, 25-34 (1998)

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